Barenaked Ladies man survives plane crash

Barenaked Ladies singer Ed Robertson and three others are fine after organism involved in a woodworking plane crash in Canada yesterday.


The float-plane, which Robertson was reportedly pilotage, went low in the woods near Bancroft yesterday afternoon, as it time-tested to take off from Baptiste Lake.


The woodworking plane reportedly confused airspeed, then crashed.


A police force official aforementioned everyone on board is fine, merely refused to give details of wHO was on the aeroplane, and did not confirm who was piloting, although intelligencer.ca reports that locals sound out it was Roberston himself.


An investigation has been launched by Canada's Transportation Safety Board.

--By our New York staff.
Find out more about NME.



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Madonna World Tour To Be Cancelled?

...more Madonna �

Madonna's approaching world tour has been thrown into turmoil after the pop superstar injured her ankle joint, just two weeks before the alive shows ar due to kick off.


The almost 50-year old is currently in New York rehearsing for her Sticky & Sweet tour which will begin in Cardiff Wales on 23 August.


And she was photographed this weekend nursing a heavily bandaged foot, prompting fears that she may non be in full fit for the first base date of the tour.


The mammoth trek will address Europe and North America and will wrap up in Mexico City on 30 November.

Wideboys

   
Artist: Wideboys

   Genre(s): 
Other
   

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Discography:


   
 The Freak

   Year: 2004   
Tracks: 4

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Landmark Studies To Assess Risk Of Exposure To Elevated Levels Of EMS Confirm Clear Toxicity Threshold For DNA Damage

News Tips From The Journal Of Neuroscience

�1. Hodgkin CHuxley Model of Backpropagating Spikes




Yuguo Yu, Yousheng Shu, and David A. McCormick





Axon potentials recorded in somata of pyramidal neurons in vivo have a libertine rising form and variable threshold, contrary to predictions of the Hodgkin�CHuxley simulation. Some have suggested that this difference is due to cooperativity among atomic number 11 channels, resulting in many channels opening simultaneously. Yu et al. now show that the shape and threshold variance of somatic action potentials can be explained by the fact that spikes backpropagate to the frame from their initiation point, ~40 ��m along the axon. Simultaneous intracellular recordings from somata and axons in cortical slices revealed that the shape and threshold unevenness of spikes at the spike-initiating zone were logical with predictions of the Hodgkin�CHuxley framework. Computer simulations confirmed that the resurrect times of spikes in the sarcostemma acidum were influenced by backpropagation, and that threshold unevenness resulted from differences in membrane potential in the soma and axon initial segment at the time of spike initiation.





2. SCLIP Role in Purkinje Cell Dendritogenesis




Fabienne E. Poulain, St�phanie Chauvin, Rosine Wehrl� Mathieu Desclaux, Jacques Mallet, Guilan Vodjdani, Isabelle Dusart, and Andr� Sobel





Purkinje cells develop highly forked dendritic arbors that get tens of thousands of synaptic inputs. Poulain et al. reputation this week that SCLIP, a member of the stathmin household of microtubuledestabilizing proteins, is important in Purkinje cadre dendritogenesis. In the developing cerebellum, SCLIP was explicit primarily in Purkinje cells, became saturated in dendrites as they formed, and decreased when the dendritic arbor was fully formed. The expression was concentrated in the Golgi setup and other vesicular structures. Overexpression of SCLIP in postnatal organotypic cerebellar cultures accelerated dendritic development and increased the number and branching of primary dendrites. Conversely, early knockdown of SCLIP via RNA suppression inhibited the initial formation of dendrites, and subsequently knockdown inhibited growth and branching of nascent dendrites. Importantly, contiguous Purkinje cells that were not transfected with meddling RNAs highly-developed normally, indicating that SCLIP affects dendritogenesis only in the cadre in which it is expressed.





3. Stress and Cannabinoids




Silvia Rossi, Valentina De Chiara, Alessandra Musella, Hajime Kusayanagi, Giorgia Mataluni, Giorgio Bernardi, Alessandro Usiello, and Diego Centonze





The human relationship between tension and the endocannabinoid scheme are building complex, and energizing of cannabinoid receptors tin can have divers and apparently contradictory personal effects on the stress response. This complexity is further demonstrated this week by Rossi et al., world Health Organization show that stress has different effects on GABAergic and glutamatergic transmission in the striatum, a brain area that has heights levels of cannabinoid receptors and is important in stress responses. Mice were subjected everyday to an aggressive male to hasten social stress, and the effects of exogenous and endogenous cannabinoids were measured in corticostriatal slice cultures. Stress exposure eliminated the reductions in GABAergic IPSC frequency and amplitude that are normally produced by cannabinoids. In contrast, stress did non alter cannabinoid-mediated reduction in glutamatergic EPSC frequency and amplitude. Providing mice with rewards (exercise, sugar, or cocaine) subsequently social stress eliminated the effects of stress on cannabinoid modulation of GABAergic transmission.





4. Voltage-Gated Sodium Channel Mutations in Migraine




Sandrine Cest��le, Paolo Scalmani, Raffaella Rusconi, Benedetta Terragni, Silvana Franceschetti, and Massimo Mantegazza





Different mutations in the neuronal voltage-gated sodium channel (Nav1.1) drive familial hemiplegic migraine (FHM) or epilepsy. To assist differentiate the physiological bases of these diseases, Cest��le et al. expressed human Nav1.1 channels bearing the FHM case 3 mutation (which results in an amino acid substitution in the inactivation gate) in a non-neural cell line and in cultured neocortical neurons. The electrophysiological properties of the mutant line were consistent with it conferring a limited hyperexcitability on neurons. Compared to wild type, mutated channels had a positive shift in the voltage habituation of deactivation, reduced upper limit current denseness, and quicker inactivation. Some of these properties are expected to produce hyperexcitability, and others should party favor hypoexcitability. Mutant channels appeared able to sustain high frequency firing better than wild-type channels, only this ability was limited and disappeared after sustained depolarization. This limited hyperexcitability may tell migraine and epilepsy mutations.









Please click here for the current table of contents.





Source: Sara Harris



Society for Neuroscience




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Naildown

   
Artist: Naildown

   Genre(s): 
Metal
   

---

Discography:


   
 World Domination

   Year: 2005   
Tracks: 10

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The 'Bourne' marketing ploy

Johnny Copeland

   
Artist: Johnny Copeland

   Genre(s): 
Blues
   Rock
   

---

Discography:


   
 Ghetto Child

   Year: 2001   
Tracks: 14


   
 Live In Australia [1990]

   Year: 1997   
Tracks: 10


   
 Jungle Swing

   Year: 1996   
Tracks: 11


   
 Texas Twister

   Year: 1990   
Tracks: 15


   
 Showdown!

   Year: 1985   
Tracks: 9

---

Considering the quantity of time he spent steadily pealing from gig to gig, Johnny "Clyde" Copeland's prove to prominence in the vapors world in the early '90s wasn't all that surprising. A contract with the PolyGram/Verve label put his '90s recordings into the hands of thousands of blue devils lovers around the world. It's non that Copeland's gift changed all that a good deal since he recorded for Rounder Records in the 1980s; it's simply that major companies began to ascertain the voltage of dandy, tireless megrims musicians like Copeland. Unfortunately, Copeland was forced to dull down in 1995-96 by heart-related complications, in time he continued to perform shows until his demise in July of 1997.


Greyback Copeland was born March 27, 1937, in Haynesville, LA, around 15 miles south of Magnolia, AR (erst Texarkana, a hotbed of blues activity in the 1920s and '30s). The word of sharecroppers, his begetter died when he was selfsame thomas Young, simply Copeland was tending his father's guitar. His low gig was with his friend Joe "Guitar" Hughes. Soon after, Hughes "took sick" for a workweek and the cy Young Copeland discovered he could be a front man and cede vocals as comfortably as anyone else around Houston at that sentence.


His music, by his have reasoning, fell somewhere between the smelly R&B of New Orleans and the swing and leap blues of Kansas City. After his family (sans his begetter) moved to Houston, Copeland was uncovered, as a teenager, to musicians from both cities. While he was becoming interested in music, he also chased boxing, by and large as an avocation, and it is from his years as a boxer that he got his nickname "Clyde."


Copeland and Hughes fell under the spell of T-Bone Walker, whom Copeland low saw perform when he was 13 age old. As a teen he played at locales such as Shady's Playhouse -- Houston's preeminent blues club, horde to well-nigh of the city's best bluesmen during the fifties -- and the Eldorado Ballroom. Copeland and Hughes later formed The Dukes of Rhythm, which became the house band at the Shady's Playhouse. After that, he worn-out time playing on circuit with Albert Collins (himself a cuss T-Bone Walker lover) during the fifties, and besides played on stage with Sonny Boy Williamson II, Big Mama Thornton, and Freddie King. He began recording in 1958 with "Rock 'n' Roll Lily" for Mercury, and touched between several labels during the 1960s, including All Boy and Golden Eagle in Houston, where he had regional successes with "Please Let Me Know" and "Downhearted on Bending Knees," and later for Wand and Atlantic in New York. In 1965, he displayed a surprising prescience in terms of the pop market by cut a version of Bob Dylan's "Blowin' in the Wind" for Wand.


After touring around the "Lone-Star State triangle" of Louisiana, Texas and Arkansas, he resettled to New York City in 1974, at the top of the disco boom. It seems moving to New York City was the c. H. Best vocation move Copeland ever made, for he had easy access code to clubs in Washington, D.C., New York, Philadelphia, New Jersey, and Boston, all of which tranquil had a spot for blues musicians like him. Meanwhile, gage in Houston, the baseball club scene was hurting, undischarged partially to the oil-related recession of the mid-'70s. Copeland took a day job at a Brew 'n' Burger restaurant in New York and played his blues at dark, finding centripetal audiences at clubs in Harlem and Greenwich Village.


Copeland recorded sevener albums for Rounder Records, showtime in 1981 and including Copeland Special, Make My Home Where I Hang My Hat, TX Twister, Delivery It All Back Home, When the Rain Starts a Fallin', Ain't Nothing But a Party (live, nominative for a Grammy) and Boom Boom; he likewise won a Grammy award in 1986 for his efforts on an Alligator album, Encounter! with Robert Cray and the late Albert Collins. Although Copeland had a booming, shouting voice and was a powerful guitar player and live performer, what most people don't realize is just how clever a songster he was. His latter-day releases for the PolyGram/Verve/Gitanes mark, including Flyin' High (1992) and Catch Up with the Blues, supply ample grounds of this on "Life's Rainbow (Nature Song)" (from the latter record album) and "Luck" (from the onetime record album).


Because Copeland was only six months old when his parents split up and he alone byword his male parent a few multiplication before he passed away, Copeland never completed he had transmissible a innate heart shortcoming from his male parent. He disovered this in the midst of some other typically hectic circuit in late 1994, when he had to go into the hospital in Colorado. After he was diagnosed with heart disease, he spent the next few age in and out of hospitals, undertaking a number of dear nerve surgeries. Early in 1997, he was waiting for a bosom graft at Columbia Presbyterian Medical Center in New York City. As he was waiting, he was assign on the L-VAD, a recent innovation for patients hurt from congenital nerve defects. In 1995, Copeland appeared on CNN and ABC-TV's Adept Morning America, wearing his L-VAD, offering the conception valuable publicity.


Scorn his health problems, Copeland continued to do and his always bouncy concerts did not diminished all that a great deal. After living 20 months on the L-VAD -- the longest anyone had lived on the device -- he received a heart transplant on January 1, 1997 and for a few months, the bosom worked fine and he continued to tour. However, the middle developed a defective valve, necessitating nerve operating theater in the summer. Copeland died of complications during middle surgery on July 3, 1997.

Cranford leads TV BAFTAs shortlist

BBC costume drama 'Cranford' leads the BAFTA Television Awards shortlist with four nominations.
The show and its stars will contest the categories of Best Serial Drama, the Audience Award and Best Actress, with both Judi Dench and Eileen Atkins nominated in this category.
The other shows nominated for the Audience Award this year are 'The Apprentice', 'Andrew Marr's History of Modern Britain', 'Britain's Got Talent', 'Gavin and Stacey' and 'Strictly Come Dancing'.
Joining Dench and Atkins on the Best Actress shortlist are Gina McKee, for her role in 'The Street', and Kierston Wareing, for her role in 'It's a Free World'.
Also nominated in the Best Drama Serial category, alongside 'Cranford', are 'Britz', 'Five Days' and 'Murphy's Law'.
The nominees for the Best Actor award are Andrew Garfield for 'Boy A', Tom Hardy for 'Stuart: A Life Backwards', Matthew Macfadyen for 'Secret Life' and Antony Sher for 'Primo'.
The shortlist for the Best Continuing Drama award includes 'The Bill', 'EastEnders', 'Emmerdale' and 'Holby City'.
Contesting the award for Best Interactivity Show are 'Big Art Mob', 'Doctor Who Comic', 'Spooks Interactive' and 'The X Factor'.
Nominated for Best Entertainment Programme are 'Britain's Got Talent', 'Harry Hill's TV Burp', 'Have I Got News for You' and 'Strictly Come Dancing'.
The nominees for Best Comedy Programme are 'The Armstrong & Miller Show', 'Fonejacker', 'Russell Brand's Ponderland' and 'Star Stories'.
Nominated in the category of Best Entertainment Performance are Simon Amstell for 'Never Mind the Buzzcocks', Alan Carr & Justin Lee Collins for 'The Friday Night Project', Stephen Fry for 'QI' and Harry Hill for 'Harry Hill's TV Burp'.
In the running for the Best Comedy Performance award are Peter Capaldi for 'The Thick of It', James Corden for 'Gavin and Stacey', Stephen Merchant for 'Extras Christmas Special' and David Mitchell for 'Peep Show'.
'Boy A', 'Coming Down the Mountain', 'The Mark of Cain' and 'The Trial of Tony Blair' have been nominated for Best Single Drama.
The nominees for Best Drama Series are 'Life on Mars', 'Rome', 'Skins' and 'The Street'.
In the running for Best International Show are 'Californication', 'Family Guy', 'Heroes' and 'My Name Is Earl'.
The winners will be announced at a ceremony at the London Palladium on 20 April, broadcast on BBC1.
For a full list of the BAFTAs TV Awards nominees click here.